Architecture of a basic biosensor
It is commonly made up of three components
· The sensitive biological element (e.g. tissue, microorganisms, organelles, cell receptors, enzymes, antibodies, nucleic acids, etc.), a biologically derived material or bio-mimetic component that interacts (binds or recognizes) the analyte under study. The biologically sensitive elements can also be created by biological engineering.
· The transducer or the detector element (works in a physicochemical way; optical, piezoelectric, electrochemical, etc.) that transforms the signal resulting from the interaction of the analyte with the biological element into another signal (i.e., transduces) that can be more easily measured and quantified;
· Biosensor reader device with the associated electronics or signal processors that are primarily responsible for the display of the results in a user-friendly way. This sometimes accounts for the most expensive part of the sensor device, however it is possible to generate a user friendly display that includes transducer and sensitive element. The readers are usually custom-designed and manufactured to suit the different working principles of biosensors.
(Ref. no - 5)
· The sensitive biological element (e.g. tissue, microorganisms, organelles, cell receptors, enzymes, antibodies, nucleic acids, etc.), a biologically derived material or bio-mimetic component that interacts (binds or recognizes) the analyte under study. The biologically sensitive elements can also be created by biological engineering.
· The transducer or the detector element (works in a physicochemical way; optical, piezoelectric, electrochemical, etc.) that transforms the signal resulting from the interaction of the analyte with the biological element into another signal (i.e., transduces) that can be more easily measured and quantified;
· Biosensor reader device with the associated electronics or signal processors that are primarily responsible for the display of the results in a user-friendly way. This sometimes accounts for the most expensive part of the sensor device, however it is possible to generate a user friendly display that includes transducer and sensitive element. The readers are usually custom-designed and manufactured to suit the different working principles of biosensors.
(Ref. no - 5)
a biosensor should be
· Small, of a size appropriate for use.
· Manufacturable in large numbers and at low cost
· Rapid.
· Result within the timescale of the process/diagnostic test
· Economical. Low cost of ownership
· Always considered as a sensor system with the instrument
· Self calibrating.
· Minimal action by user.
· Probably single use
(Ref no 6)
· Manufacturable in large numbers and at low cost
· Rapid.
· Result within the timescale of the process/diagnostic test
· Economical. Low cost of ownership
· Always considered as a sensor system with the instrument
· Self calibrating.
· Minimal action by user.
· Probably single use
(Ref no 6)